SOIL RECYCLING AMONG CONSTRUCTION SITES BY OPTIMIZING SCHEDULE AND COSTS FOR EARTHMOVING




Impressive and durable clinical responses obtained with dabrafenib and trametinib in low-grade serous ovarian cancer harbouring a BRAF V600E mutation

Low-grade serous ovarian cancer (LGSOC) is now considered a different entity from high-grade Lampshade serous ovarian cancer.The chemoresistance inherent to this type of ovarian cancer narrows the therapeutic options, especially in the recurrent setting.It is thought that the mitogen-activated protein kinase (MAPK) pathway plays a significant role

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Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs

The designer proline-rich antimicrobial peptide (PrAMP) Chex1-Arg20 amide (ARV-1502) is active against Gram-negative and Gram-positive pathogens in different murine infection models when administered parenterally and possesses a wide therapeutic index.Here we studied the pharmacokinetics of ARV-1502 for the first time when administered intramuscula

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